1.Hepatitis C vaccine prevention There is no effective vaccine to prevent hepatitis C. 2. Strict screening of blood donors Strictly implement the Blood Donation Law of the People’s Republic of China and promote blood donation without compensation. Strictly screen blood donors by testing serum anti-HCV and alanine aminotransferase (ALT). The detection method of HCV antigen should be developed to improve the detection rate of window stage infected patients. 3. Prevention of transdermal and mucosal route transmission Promote safe injection. Medical instruments such as dental instruments and endoscopes should be strictly disinfected. Medical personnel should wear gloves when touching patients’ blood and body fluids. Provide psychological counseling and safety education to intravenous drug users to persuade them to quit drugs. Do not share razors and dental instruments, etc. Haircutting tools, piercing and tattooing tools should be strictly disinfected. 4. Prevention of sexual transmission Those with a history of sexual promiscuity should be examined regularly and management should be strengthened. It is recommended that HCV-infected persons use condoms during sexual intercourse. Proper sex education should be provided to adolescents. Prevention of mother-to-child transmission Pregnant women with positive HCV RNA should avoid amniocentesis, minimize the delivery time, ensure the integrity of the placenta, and reduce the chance of exposing the newborn to maternal blood.