At present, there is a lack of particularly effective treatments for chloasma, which can be lightened by removing the causes, medication and physical therapy. 1. Remove the causes: Melasma is related to genetic factors, ultraviolet radiation, sex hormone level, disease factors and so on. It is suggested that patients should avoid direct sunlight and take appropriate sun protection measures when going out; use anti-allergic and moisturizing medical skincare products to promote the repair of skin barrier function; actively treat liver disease, gynecological disease, and other diseases that may lead to melasma; and take a regular work and rest schedule and have a reasonable diet. 2. Medication: When general treatment is not effective, medication can be considered. Common topical medicines include hydroquinone cream, azelaic acid, retinoic acid, etc., which may lead to itching, tingling, erythema, swelling and other adverse reactions; oral vitamin C, vitamin E, tranexamic acid, glutathione and other medicines can inhibit melanin synthesis and lighten melasma, and can be combined with other medicines. 3. Physical treatment: Fractional laser, picosecond and other physical treatments are effective for melasma, but it requires multiple treatments. It is recommended that chloasma patients should go to regular medical institutions in time when the symptoms do not get better or when the symptoms are serious after taking some measures to remove the causes of the disease, and choose appropriate treatment plans under the guidance of specialists, avoiding the use of medicines privately, so as to avoid delaying the condition.