The closure of the vaginal opening is usually due to the long-term inflammation of the vulva, so that the labia minora localized oozing more, which caused the adhesion of the mucous membrane so that the vaginal opening is closed. In this case, it is recommended to separate the adherent tissues under local anesthesia, and actively give anti-inflammatory treatment, and in the adherent localization can be coated with estriol ointment, to promote the healing of the local mucous membrane as soon as possible, which makes the phenomenon of vaginal closure can be relieved. In addition, it is recommended to pay attention to personal hygiene, it is best to use water to wash the vulva twice a day, especially during menstruation, pay attention to change sanitary napkins, to avoid the infection of pathogenic bacteria.