Rectal ulcer usually does not cause inflammation of the terminal ileum. Because the main clinical manifestations of rectal ulcer are abdominal pain, diarrhea, pus and blood stools, constipation, stool thinning, etc. If acute onset of the disease, blood in the stool, severe abdominal pain, and even intestinal perforation, acute hemorrhage, intestinal necrosis and other serious complications. Inflammation of the terminal ileum can be caused by bacterial infection or autoimmune disease, i.e. Crohn’s disease. Inflammation of the terminal ileum may lead to narrowing of the intestinal lumen or even complete obstruction because it is a proliferative change; it may also lead to repeated blood in the stool due to ulceration, resulting in anemia, hypoproteinemia, malnutrition, and wasting. Patients suffering from rectal ulcer or inflammation of the terminal ileum should go to the hospital in time and do a comprehensive examination under the guidance of the doctor, and then according to the history, physical examination, laboratory tests, imaging, endoscopy, etc. in order to make a clear diagnosis and timely treatment.