There are many drugs to stabilize plaque, the most typical drugs are antiplatelet drugs, statin lipid-lowering drugs, PCSK9 inhibitors, etc. However, there is no such thing as the “best” drug, it is best to use the right drug according to the doctor’s instructions. However, therapeutic drugs should follow the principle of individualization, there is no such thing as the “best” drug, and it is best to use the appropriate drug as prescribed by the doctor. 1. Antiplatelet drugs: Such as aspirin, clopidogrel bisulfate tablets, Tegretol, etc. Tegretol is a relatively new drug, the effect is also better. 2. Statin lipid-lowering drugs: Like Rosuvastatin, Atorvastatin and so on. Statin drugs, is currently the most effective lipid-lowering drugs, not only can strongly reduce the total cholesterol (TC) and low-density lipoprotein (LDL) levels, but also can reduce triglycerides (TG) to a certain extent, elevate the level of high-density lipoproteins (HDL), so statins can also be called a more comprehensive lipid-regulating drugs. 3. PCSK9 inhibitors: Eloxizumab: Used for the treatment of familial hypercholesterolemia in adults or adolescents 12 years of age or older with a pure subtype of hypercholesterolemia. Reduces the risk of myocardial infarction, stroke, and coronary revascularization in adult patients with preexisting atherosclerotic cardiovascular (ASCVD) disease. For the treatment of primary hypercholesterolemia (including heterozygous familial hypercholesterolemia) and mixed dyslipidemia in adults. It should be used in accordance with the doctor’s instructions, avoid self-medication, prohibited for allergic people, and should pay attention to a healthy lifestyle and so on.