Nimesulide Extended-Release Tablets have the efficacy and effect of relieving pain and other uncomfortable symptoms caused by chronic arthritis and other diseases. Nimesulide extended-release tablets is a kind of non-steroidal anti-inflammatory drug, mainly plays the role of analgesic, anti-inflammatory, the drug is only used after the ineffective treatment with other non-steroidal anti-inflammatory drugs, it can relieve chronic arthritis, such as osteoarthritis, acute trauma, surgery, pain and inflammation, but also can be used for primary dysmenorrhea. The drug can have adverse reactions such as stomach pain, heartburn, gastrointestinal dysfunction, analgesic drugs should be avoided during the use of the drug and should not be used in combination with other non-steroidal anti-inflammatory drugs. It may interact with furosemide, toluene sulfobutylurea, salicylic acid, fenofibrate and other drugs, so you should consult a medical professional before use. It is contraindicated in the following cases: allergy to the drug or other NSAIDs; history of gastrointestinal perforation and bleeding after using NSAIDs; active gastrointestinal bleeding, ulcers, or previous history of recurrent bleeding and ulcers; cerebrovascular hemorrhage, bleeding disorders, etc.; severe coagulation disorders, heart failure, or hepatic or renal impairment; perioperative period of coronary artery bypass grafting surgery. If you need to use the drug patients, please be sure to strictly comply with the doctor’s instructions under the guidance of the medication, do not self-medication.