The typical manifestation of thyroiditis is sometimes pain, not necessarily a bad phenomenon, but also need to be combined with other clinical manifestations, laboratory tests to comprehensively assess the severity of the disease. Thyroiditis is a heterogeneous disease that involves the thyroid gland and is caused by autoimmunity, viral infections, bacterial or fungal infections, radiation damage, drugs, trauma, and other causes of follicular destruction of the thyroid gland, resulting in inflammation. Subacute thyroiditis, Hashimoto’s thyroiditis, and acute suppurative thyroiditis are common. Thyroiditis can show symptoms such as enlargement of the thyroid gland, pain, fatigue, fever and so on. Therefore, thyroiditis pain is not necessarily a bad phenomenon, should be combined with other clinical manifestations, laboratory tests to comprehensively assess the severity of the disease. It is recommended that patients with thyroiditis go to the hospital in time and follow the doctor’s instructions for treatment to avoid delaying the condition.