I. Overview: When an infant has high jaundice, pay attention to distinguish whether it is physiological jaundice or pathological jaundice. Physiological jaundice does not require treatment, while pathological jaundice needs to be treated by a doctor. 1. If the child is in very good condition, full term, eating milk and having a good temperature, it is physiological jaundice and does not need treatment, just ensure adequate feeding. The American Academy of Pediatrics recommends breastfeeding 8-12 times a day to promote active digestion and excretion in the baby, to speed up the excretion of bilirubin and reduce reabsorption back into the bloodstream. 2, If the child develops jaundice within 24 hours after birth or jaundice develops too quickly and lasts for a long time, even accompanied by anemia, abnormal body temperature, poor feeding, vomiting, abnormal color of urine and stool. In some cases, the jaundice has subsided or reduced and then reappeared and aggravated, mostly pathological jaundice. 3, when pathological jaundice appears, you must go to the hospital to receive treatment, otherwise it will leave sequelae or even life-threatening. Treatment of pathological jaundice mainly has light therapy, blood exchange therapy and drug therapy. Second, drug treatment: must be taken under the doctor’s orders. 1, enzyme inducers: phenobarbital, side effects include drowsiness and slow sucking milk. 2, glucocorticoids: available prednisone or dexamethasone, but should be used carefully according to the cause of jaundice. Third, blue light treatment 1, it is generally believed that the wavelength of 440-470nm blue light on the strongest effect of bilirubin, it can make bilirubin oxidation into a non-toxic water-soluble products, so that the jaundice deposited in the skin as soon as possible through the stool, urine out of the body, so this method is commonly used to treat baby jaundice. 2, blue light irradiation therapy is recognized as a safe treatment for neonatal hyperbilirubinemia. First, let the baby lie in the phototherapy box, cover both eyes and genital organs and leave the rest exposed, then irradiate with blue light. 3.Clinically, intermittent blue light irradiation is mostly used, stopping after 4-8 hours of irradiation, while monitoring the bilirubin level until the bilirubin drops to within the normal range, and then deciding whether to stop the treatment according to the neonatal hourly bilirubin curve. 4. For children with congenital abnormalities of bilirubin metabolism, their bilirubin level is easy to repeat, and the irradiation time should be relatively longer. IV. Intravenous infusion of albumin: such as injection of Niclosamide to adsorb the bilirubin in the serum and then excrete it from the body. Five, blood exchange therapy: blood exchange is the most rapid and effective method of neonatal jaundice, but blood exchange requires high medical technology and is expensive, and not every jaundiced baby is suitable for blood exchange therapy, and this therapy may also produce some adverse reactions, so this therapy is mainly used for babies with severe pathological jaundice.