When kidney cancer is inoperable, drug treatment and withholding surgery should be chosen according to specific reasons. Drug treatment: it is adapted to patients with metastatic kidney cancer. Such as metastatic or unresectable clear cell renal cancer, they can choose to use Sunitinib, Sorafenib, Cabotinib, Axitinib, Bevacizumab and other drugs for treatment. Some kidney cancer patients have lesions that can be removed by surgery, but they cannot tolerate the surgery due to the poor basic condition of the whole body, such as the poor tolerance of heart and lungs. In this case, the function of heart and lungs should be adjusted first, and then surgery will be performed after their function is strengthened and they can tolerate the surgery. For kidney cancer patients, after diagnosis, they should actively cooperate with doctors for treatment, which can effectively increase the survival period of patients, while their family members should give them more company.