In general, there are no specialized medications to treat a particular condition. Calcification is a very small localized lesion of the prostate, and usually no medication is needed if only calcification is targeted. However, patients with prostate enlargement accompanied by calcification can be treated with drugs such as 5α reductase inhibitors, α-blockers, and M-receptor antagonists, depending on the specific condition. 1. 5α reductase inhibitors: such as finasteride, dutasteride, etc. This kind of drugs can inhibit the chemical transformation of testosterone to dihydrotestosterone, and radically reduce the rate of prostate hyperplasia, so as to achieve the purpose of partially reducing the size of the prostate. 2. α-blockers: such as doxazosin, terazosin, tamsulosin, etc., mainly through the relaxation of smooth muscle, in order to help alleviate the problem of power obstruction at the outlet of the bladder, in order to improve the prostate enlargement. 3. M-receptor antagonists: such as Tolterodine, Oxybutynin, Solifenacin, etc. Such drugs can help relieve the over-contraction of the urethral muscle, so that the bladder sensitivity is reduced, which in turn improves the symptoms of patients with prostatic hyperplasia such as frequent urination and urinary urgency. Different patients have different symptoms, causes and severity of prostate enlargement and calcification, so it is recommended to use the right medication to implement the treatment under the guidance of a doctor.