Utero-ovariectomy, long-term use of glutamine and vitamin B1 is generally not recommended to avoid damage to health. 1. Glutamine: generally used to regulate endocrine dysfunction and treatment of autonomic dysfunction, once long-term use, it is easier to induce nausea, vomiting, hair loss, dry mouth, skin itching and gastrointestinal discomfort. So generally require patients to take time not more than 3 weeks, for glutamine allergy is prohibited, gastric ulcer patients should be used with caution. 2. Vitamin B1: used in the treatment of vitamin B1 deficiency induced peripheral neuropathy and dyspepsia and other symptoms of adjuvant therapy, long-term overdose may cause headache, convulsions and arrhythmia and other adverse reactions, generally recommended that the course of treatment should not exceed 12 months. Vitamin B1 should not be taken with aspirin and alkaline drugs such as aminophylline. Therefore, the application of glutamine and vitamin B1 need to get the guidance of a specialist, patients should not blindly take the drug.