Walking out of the blisters can be based on the size and character of the blisters to choose their own observation or puncture fluid extraction and other methods of treatment. 1. Smaller blisters: If the blisters are smaller, they can be treated without treatment, and the body can absorb and subside on its own. 2. Larger blisters: If the blisters are larger, with obvious fluid accumulation in the epidermis, tighter walls, and localized swelling and discomfort, a professional doctor is required to puncture the blisters with a sterile syringe in a sterile environment, extract the fluid, and apply pressure bandage to the puncture site. If there are symptoms of redness, swelling and pain around the blister gradually after the blister fluid is extracted, the treatment of infection prevention should also be strengthened, such as topical fusidic acid cream, mupirocin ointment and other drugs. When walking blisters need to protect the blisters, once the breakage occurs, you need to follow the doctor’s instructions to use drugs to prevent infection. If the blisters are large, patients are advised to handle them under the guidance of a professional doctor to avoid infection caused by improper operation.