The length of life of a patient with dryness cannot be generalized, but depends on the severity of the patient’s condition and treatment. Dryness is a kind of chronic inflammatory autoimmune disease, mostly seen in women. In the early stage, it often invades lacrimal glands, salivary glands and skin mucosal exocrine glands, and patients show dry mouth and eyes, and in the late stage, it easily invades lungs, liver and kidneys. After reasonable treatment, the survival time of early stage patients is not significantly different from that of normal people, and they can live and study normally. Patients with visceral damage can also significantly improve their condition with effective treatment, and patients have a better prognosis. If patients do not undergo effective treatment and the disease develops to the middle and late stages, with serious complications such as progressive pulmonary fibrosis, central nervous system lesions, renal insufficiency or combined malignant tumors, the prognosis is worse and the survival time will be greatly shortened. Therefore, it is recommended that patients with dryness must go to the rheumatology department of the hospital for clear diagnosis and effective treatment in order to improve the quality of life and life expectancy of patients.