Men masturbation is generally not harmful, if long-term frequent masturbation, may lead to glans, prostatitis, erectile dysfunction, premature ejaculation and other diseases. 1. glans:glans is due to bacteria, fungi and other pathogens infection or their own disease, patients will appear glans skin mucosa edema, erosion, urination pain and other symptoms. If you masturbate often, you may bring bacteria and other pathogens into the glans, causing glansitis. 2. Prostatitis:Prostatitis is caused by bacterial infection and other factors, the patient’s main symptoms are urinary urgency, urethral dribbling, urinary frequency. The patient’s long-term masturbation may lead to aseptic prostatitis. 3. Erectile dysfunction:Erectile dysfunction has many causes, mainly due to psychological factors and their own diseases. The main symptoms of the patient are difficult to get an erection, slow erection and so on. Prolonged masturbation can cause the penis to be in a state of congestion and erection for a long time, which will lead to the patient’s sexual nerve fatigue and thus erectile dysfunction. 4. Premature ejaculation: Premature ejaculation is usually caused by psychological or mental factors, patients will be unable to control the ejaculation time, premature ejaculation and other symptoms. If the patient often masturbate, it will lead to the phenomenon of premature ejaculation. Masturbation for men is normal and harmless. If frequent masturbation, not only may lead to sexual dysfunction, but also may affect the patient’s mood as well as psychological, it is recommended that the patient appropriate masturbation.