Common causes of pustules on hands and feet include impetigo and palmoplantar impetigo. 1. Impetigo:This disease is mainly dominated by Staphylococcus aureus infection, followed by type B hemolytic streptococcus infection, which can generally be transmitted through direct contact or self-inoculation. Higher temperature, more sweating and skin maceration can promote the local reproduction of bacteria, thus inducing impetigo. When it occurs on the hands and feet, pustules appear on the skin of the hands and feet. 2. Palmoplantar pustulosis:This disease belongs to pustular psoriasis, which can be induced by genetic factors and environmental factors under the joint action of the body’s immunity decline, the lesions are limited to the palms of the hands and feet and metatarsals, and pustules appear on the basis of erythema. After the pustules on the hands and feet, it is recommended that the patients go to the dermatology department of the regular hospital in time according to their own conditions, follow the doctor’s instructions to make a clear diagnosis and timely treatment to avoid delaying the condition.