Based on the experience accumulated in the treatment of papillary thyroid carcinoma over the past few years, we would like to present our personal understanding of papillary thyroid carcinoma: 1. Whether isotope (iodine 131) therapy is necessary after surgery for papillary thyroid carcinoma The overall therapeutic effect of isotope therapy is about 75% for papillary thyroid carcinoma and 100% for follicular thyroid carcinoma. Isotopes are relatively effective for ablation of residual thyroid gland after surgery for papillary thyroid cancer and for distant metastatic lesions such as lung. However, in the case of papillary thyroid cancer, if it is not completely eradicated intraoperatively and isotope treatment is performed, there may be a risk of recurrence within a short time after surgery and the need for reoperation. Therefore, it is recommended to consult with the surgeon and nuclear medicine doctor whether isotope therapy is necessary after surgery for papillary thyroid cancer. 2.Whether total thyroidectomy is necessary for papillary thyroid cancer Total thyroidectomy is the most thorough treatment for papillary thyroid cancer, and it is highly recommended in Europe, America and Japan. Some patients are concerned about the need for lifelong medication after total thyroidectomy and the side effects of taking medication. Generally speaking, whether lifelong medication is needed after thyroid surgery is related to thyroid disease: if the disease is benign, lifelong medication is generally not needed after surgery; even if lifelong medication is needed, the amount of medication will not be very large, therefore, the side effects of medication are less. In the case of papillary thyroid cancer, it is best to take medication for life, regardless of whether the thyroid gland is preserved after surgery. Moreover, in the case of papillary thyroid cancer, the dose of medication is higher and the side effects of the medication may be more pronounced because TSH needs to be controlled at a relatively low level. In short, whether or not lifelong medication is required after thyroid surgery and the side effects of medication are related to the disease of the thyroid gland, not to whether the thyroid gland is completely removed or preserved. At the same time, in the case of papillary thyroid cancer, if the thyroid gland is completely excised and there is no metastasis in the lymph nodes, there is no possibility of recurrence after surgery, therefore, TSH does not need to be controlled very low and the dose of medication may not be very high, thus reducing the side effects of medication.