Thymoma itself does not cause hiccups. If a patient develops hiccups during medical consultation or treatment, it indicates that the patient’s condition has metastasized and phrenic nerve involvement has occurred, in which case hiccups may occur, or hiccups may be caused by drug-related side effects during treatment, so the cause of the hiccups needs to be clearly identified. If drug-related hiccups are not considered during treatment, it is important to further examine whether the disease has progressed. If the existing treatment does not control the disease satisfactorily, it is necessary to change the treatment regimen or to do further comprehensive whole-body examination to determine whether there are new metastatic lesions elsewhere.