A fever of 39 degrees in adults is accompanied by significant symptoms, mainly headache, generalized muscle aches and pains, and even back pain. The most common ones are ibuprofen, acetaminophen and indomethacin. After taking antipyretic drugs, the fever can be reduced in about two hours. However, when the fever reaches 39 degrees, it is usually not caused by common cold, but may be influenza, special disease, and should be judged according to the related symptoms to belong to what disease. If it is accompanied by obvious back pain, little urination, headache, orbital pain, and red face, it may be hemorrhagic fever, and you should check urine routine, kidney function, kidney ultrasound and blood routine, as well as epidemic hemorrhagic fever antibody to determine whether it is epidemic hemorrhagic fever. If there are obvious symptoms of coughing, coughing sputum, or even chest tightness, CT of the chest needs to be checked to determine if it is pneumonia. Only when the disease causing the fever is identified can treatment be targeted, otherwise symptomatic treatment alone will only relieve the symptoms, and the fever may still recur if the disease is not treated.