Keloid is a condition in which the collagen anabolic function is out of control during the healing process of skin injury, resulting in excessive deposition of collagen fibers, also known as connective tissue hyperplasia. It is a benign skin mass of varying shape, red color and hard texture that bulges out of normal skin. It has both internal and external causes. The main internal cause is the scar body and the level of estrogen in the body, this body is mostly family genetic, most of them are cross-genetic, but not contagious; external cause is mainly caused by various types of skin injuries, even minor trauma, such as mosquito bites, vaccination, ear piercing, eyebrow tattoo, needle stick injury, etc. Li Jiang, Department of Plastic and Reconstructive Surgery, General Hospital of Jinan Military Region Treatment of keloid 1. For new small keloid, it can be treated simply with 90Sr dressing. 2.For those who have been ill for a long time and have hard keloid scars, it is advisable to remove them surgically first, and then start radiation therapy after the stitches are removed. 3.Hydrocortisone acetate or deferiprone injection is suitable for the treatment of small keloids. 4.Local surgical excision is an effective method for treating internal foci of infection in keloids. 5.Keloid scars smaller than 5cm are treated with natural repair therapy by trauma regeneration, with a success rate of over 80%.