Hepatic transient elastography is performed by vibrating the probe to emit shear waves, tracking the propagation of the shear waves through ultrasound technology and measuring the velocity, converting the rate into a stiffness value to assess liver fibrosis and the grading of the degree of fibrosis. Compared to liver puncture, liver transient elastography is non-invasive, simple, rapid, easy to perform, reproducible, safe and well tolerated, and is effective in determining the severity of liver fibrosis and steatosis, and is now widely used in clinical practice. During the course of antiviral therapy, the liver transient elastometry can also be used for regular follow-up to observe changes in the elastic stiffness of the liver, monitor the portal vein pressure and the development of hepatocellular carcinoma. However, this treatment also has certain limitations, mainly affected by liver inflammation, intrahepatic cholestasis, venous thrombosis and other related factors, and needs to be further judged in conjunction with liver function and ultrasound.