The treatment of leg folliculitis is similar to that of folliculitis in other parts of the body, and you can cooperate with your doctor to choose topical medication, oral medication and surgical intervention for relief. 1. Topical medication: Since most of the folliculitis on the legs is related to Staphylococcus aureus infection, you can work with your doctor to choose iodophor solution to apply, which can play the role of sterilization. You also need to apply fusidic acid and mupirocin ointment topically, which can play an anti-infective effect. 2. Oral medication: mainly for patients with poor results of external use, when the condition is serious, it is necessary to add oral medication, such as clindamycin, amoxicillin, cefadroxil and so on. 3. Surgical intervention: localized folliculitis, if further development, may become a larger carbuncle or boil, the doctor will choose local anesthesia, and then aseptic operation under the incision of the lesion, to draw out the pus treatment. After the diagnosis of leg folliculitis, the patient should cooperate with the doctor as soon as possible for standardized treatment, so as to reduce the adverse effects of the disease.