Cranium is a hard and indispensable bone in human body, which plays a pivotal role in the normal operation and health of human life activities. When external factors or cranial lesions occur in the cranium itself, cranial defects will cause cranial defects, which will break the normal life trajectory and reduce the quality of life. Craniosynostosis is a very common craniofacial disorder in which the local scalp is sunken due to atmospheric pressure, which may lead to intracranial pressure imbalance, brain tissue displacement, as well as reduced blood flow to the cerebral hemispheres and disturbance of cerebrospinal fluid circulation, resulting in a series of clinical manifestations, mainly including: headache, vertigo, irritability, epilepsy, unexplained discomfort and various mental disorders. Therefore, patients with cranial defects must undergo cranial repair in a timely manner. Good repair materials can improve the success rate of surgery and reduce the pain of patients. Currently, new PEEK material is used as the skull repair material for skull repair. PEEK material is shaped in three dimensions according to the patient’s cranial CT data and highly restores the physiological structure of the skull. In addition, the innovative introduction of the concept of plastic surgery, combined with the unique mesh aperture design and unique intraoperative tissue separation and reset technology, effectively avoid temporal muscle atrophy, to ensure the activity of each tissue, to ensure the symmetry of the postoperative guardian head shape, to achieve the purpose of natural and beautiful appearance.