H. pylori triple therapy refers to a regimen that uses one proton pump inhibitor plus two antibiotics to treat H. pylori infection. However, nowadays, four-combination therapy, i.e., one proton pump inhibitor, one bismuth agent, and two antibiotics, is mostly used in clinical practice. In triple therapy, the commonly used antibiotics are metronidazole, tinidazole, amoxicillin, clarithromycin and so on; proton pump inhibitors often include omeprazole, lansoprazole, rabeprazole and so on. However, nowadays, the clinic mostly adopts quadruple therapy, which is based on triple therapy, and then adds a bismuth agent, such as bismuth pectin, bismuth potassium citrate and so on. It is recommended that when Helicobacter pylori appears, go to the hospital in time, under the guidance of the doctor for treatment, and the effect of sufficient quantity and course of action is better.