High fructosamine refers to the high blood glucose level in the last 2 weeks. Fructosamine is an important indicator of human blood glucose level, which is a substance formed by the protein of human plasma during the non-enzymatic glycation of glucose to reflect human blood glucose indicators. High fructose ammonia means that the body’s regulation of blood glucose in the past 2 weeks is not very good, but it does not reflect the short-term blood glucose situation. It is recommended that such patients go to the hospital for a glucose tolerance test to see if diabetes is present and then make targeted treatment. If the high fructose ammonia is caused by a persistent increase in blood glucose indicators, it is considered to be due to diabetes mellitus. Such patients usually need to make reasonable adjustments in diet and exercise in a timely manner, and strictly prohibit the intake of high-sugar and high-calorie food to suppress the increase of blood sugar. In terms of exercise, we should do more aerobic exercises to speed up the consumption of blood glucose in the body, so that the fructosamine in the body can gradually return to the normal level.