Cyclophosphamide is one of the drugs used in the treatment of nephrotic syndrome, which is usually combined with hormone therapy, and cyclophosphamide alone is not effective. The main side effects of cyclophosphamide in most clinical use: hematuria, impaired sexual function, impaired liver function, bone marrow suppression, etc., so blood routine and liver function should be checked before applying cyclophosphamide. Generally, cyclophosphamide can be taken orally, 0.1-0.2g per day, or applied intravenously once or twice a month, according to the weight of kilograms of body weight, between 0.6-1g per month, the cumulative effect of 6-8g, which is a cumulative effect of the drug.