The probability of healing a ventricular perforation is closely related to the severity of the perforation and the size of the myocardial infarction, so its healing rate cannot be generalized. Ventricular perforation refers to perforation of the interventricular septum, which is commonly triggered by myocardial infarction and occurs due to the rupture of myocardial cells of the interventricular septum after ischemia. Common symptoms are chest tightness and chest pain, drop in blood pressure, dyspnea, cold and clammy extremities, and inability to lie flat. Perforation of the ventricular septum is clinically treated by surgery. If the diameter of septal perforation is more than 3cm, the condition is generally more serious, and the survival rate of patients is lower; the diameter of perforation is less than 1cm, after surgery and drug treatment, the condition can generally be controlled within a stable range, and most of them can survive. If the area of myocardial infarction is large, the prognosis after perforation is also poorer, and may be prone to frequent ventricular premature beats, rapid atrial fibrillation and so on. Perforation of the ventricular septum is recommended to go to a regular hospital for treatment, and a professional doctor will make a prognosis judgment and choose an appropriate treatment.