What to do if estradiol drops rather than rises at 7 weeks of pregnancy

Estradiol at 7 weeks of pregnancy is not rising but falling, the decline is not big and other aspects of the examination is normal without special treatment, the decline is bigger may be a pre-eclampsia, according to the development of the embryo to see whether the treatment of fetal preservation.
The normal value of estradiol at 7 weeks of pregnancy is about 1000~2000ng/l. After pregnancy, the level of estradiol will increase moderately, which is favorable to the thickening of the uterine lining and the embryo’s implantation and growth and development.
A slight drop in estradiol alone is normal, without other autonomous uncomfortable symptoms, and no special treatment is needed when progesterone and human chorionic gonadotropin levels are normal.
If the drop in estradiol is relatively large, accompanied by vaginal bleeding, a drop in the value of human chorionic gonadotropin, and the size of the gestational sac under the gynecological ultrasound does not correspond to the gestational week, it is considered to be due to the poor development of the embryo, the body’s hormone deficiency and other reasons leading to miscarriage with precursor signs, and should be rested in bed, and if necessary, intramuscular injections of progesterone or human chorionic gonadotropin to carry on the treatment.
After pregnancy, we should do a good job of maternity examination, and find any abnormalities timely treatment.