Many middle-aged and elderly patients with sudden vision loss are diagnosed with “age-related macular degeneration” or “age-related macular degeneration” after hospital examination. What is macular degeneration? As the name suggests, macular degeneration is a degenerative disorder of the macular region of the human eye. In young people, macular degeneration is mostly related to heredity. In middle-aged and old people, as age increases, degeneration of the macula occurs, with vitreous warts, pigment disorders in the macula, and in severe cases, hemorrhage, edema and scar formation in the macula, and this disorder mostly occurs in people over 50 years old, and the prevalence increases as age increases. Therefore, in 1967, Gass proposed the name of senile macular degeneration (SMD) based on the degenerative changes of vitreous warts, retinal pigment epithelium and choroidal capillaries in the macular region of the elderly, which was later renamed as Age-related macular degeneration (AMD). In the human eye, the retina is located at the back of the eye, just like the film of a fundus camera, and the macula is located in the center of the retina, which is the most sensitive place for human eyes to see with light, shape and color perception. AMD is one of the major causes of blindness in western developed countries. As early as the mid-1980s, a survey conducted by the Peking Union Medical College Hospital Ophthalmology Department showed that the prevalence of AMD was greater than 15% in people older than 70 years old. A recent survey done in Shanghai showed that the prevalence of AMD was 15.5% in people over 50 years old. In China, with the trend of population aging, the prevalence of AMD and the number of patients will increase year by year, which will become a serious social and public health problem, such as limitations in self-care, the inability to read, the number of falls and fractures in the elderly due to visual impairment and the psychosocial problems caused by AMD will increase greatly, and the quality of life of patients will be greatly affected. In the early stages of AMD, small yellowish-white dots, called vitreous warts, are seen under the retina, which do not affect vision. However, in many patients, AMD develops into a severe lesion that has a serious impact on vision. Because it usually develops first in one eye, it is often overlooked at first.