Venlafaxine hydrochloride is an antidepressant and anxiolytic drug, the side effects of this drug may involve more systems, but overall this drug is relatively safe, side effects or adverse reactions are still relatively mild. Some side effects may occur mainly at the beginning of the drug, and the adverse reactions can usually diminish as the drug is used for a longer period of time, such as gastrointestinal reactions, because gastrointestinal reactions may be a common type of adverse reactions to these drugs, which may lead to loss of appetite, nausea or vomiting. In addition, there may also be some side effects on the nervous system, such as dizziness, headache, insomnia, nervousness, abnormal sensation, tremor, and adverse neurological reactions that patients may experience when taking the drug. These neurological adverse reactions may also be slowly relieved with the prolongation of drug use. In addition, there may be some effects on metabolism, and patients may suffer from abnormal liver function if used for a long time. Therefore, it is advisable to monitor liver function if this drug is used for a long time. In addition, there may be some effect on blood sugar, especially for diabetic patients, it is advisable to monitor the change of blood sugar, which is a common adverse reaction during the use of the drug. In addition, this drug and other psychotropic drugs are not recommended to be discontinued suddenly, if there is a need to discontinue, it is recommended to gradually reduce the dosage. Because of the possibility of withdrawal reactions, such as anxiety, nervousness, mental confusion, drowsiness, fatigue, and abnormal sensory or gastrointestinal reactions. In short, discontinuation must be under the guidance of a doctor to reasonably reduce, stop the drug, which is venlafaxine hydrochloride this drug, side effects may involve more aspects, in the process of using the drug can closely monitor their abnormal reactions.