What factors need to be taken into account for cranial repair materials? The main cause of cranial bone repair is defects formed by removal of bone flaps in craniocerebral trauma and brain surgeries (mainly aneurysms in the acute phase, cerebral hemorrhage, etc.). Due to the change in shape of the cranial defect area, the scalp is subjected to atmospheric pressure, which causes it to sink in and compress the brain tissue. In order to restore the airtightness of the cranial cavity, to keep the physiological intracranial pressure stable and to alleviate the cranial defect syndrome. To address the absence of effective protection of brain tissue in the defect area, impaired blood supply, and abnormal cerebrospinal fluid circulation. Patients with cranial defects often have a heavy burden of thought such as insecurity, and can cause headaches, dizziness, fear of vibration and other syndromes. The longer the cranial defect, the higher the incidence of cranial defect syndrome and secondary brain damage. So for safety reasons, cranial repair is necessary. How should I choose the material? Selection of surgical materials: regardless of the type of cranial defect, it is possible to repair and treat it surgically. The choice of material for surgery also determines the comfort level of the final repair of the skull. Plexiglass and autogenous bone are rarely found on the market today. Instead, titanium mesh and peek (polyether ether ketone) are used. These two materials are also the most utilized in the clinic and have the best feedback. Each material has its own advantages and disadvantages. Titanium mesh is cheaper, but there are a lot of pitfalls, because the material of titanium mesh does not have a better compatibility with the human cranium. The titanium mesh material, being a metal, expands and contracts with heat and conducts heat quickly, making the head sensitive to heat and cold. This may cause problems for patients during the change of seasons. And peek material can solve these problems perfectly. Polyether ether ketone material is more compatible with human skull. It is not sensitive to heat or cold, so there is no need to worry about the impact of the material on the scalp when the seasons change or when the temperature changes abruptly. It is also one of the most widely used materials for cranial bone repair in medicine and is also one of the most suitable materials for cranial bone repair surgery. It is strong but flexible and resilient, more resistant to impacts and better protected. It is also more comfortable. It has strong thermal insulation properties. There will be no sensitivity to hot or cold reactions. There will also be no infection after surgery and no rejection. Rays are transmissible and no artifacts are formed. A more important point is that polyether ether ketone is a material that can be three-dimensionally plasticized and can be customized for three-dimensional reconstruction according to the different needs of patients. According to the patient’s brain CT data for the design, the use of 3D printing technology to produce a perfect match with the bone window of the skull after the repair of the skull and their own skull is basically no difference. However, there are not many hospitals that do cranial bone repair with peek at present. It is also a high demand for the technology and professionalism of the doctors who are engaged in doing peek skull repair in China. Therefore, if you need this treatment, it is recommended to choose a more authoritative hospital.