Osteoarthritis has long been recognized as a degenerative disease occurring in the elderly population, a group of diseases with different etiologies but similar biological, morphological and clinical features. Among them, the incidence is higher in the knee. Knee OA refers to a degenerative disease in which primary or secondary degeneration and structural disorders occur in the cartilage of the articular surface of the knee joint, accompanied by subchondral osteophytes and cartilage exfoliation, resulting in the gradual destruction and deformation of the joint, and ultimately the occurrence of knee dysfunction, which leads to pain and disability that seriously impairs the quality of life of patients and has become one of the serious socioeconomic burdens faced by society. As our population gradually enters the ageing era, the incidence of OA is also expected to increase. First, the introduction of osteoarthritis of the knee is a common chronic degenerative osteoarthropathy, also known as proliferative knee osteoarthritis, age-related knee osteoarthritis. The clinical onset is most common in middle-aged and elderly people, with more women than men. The etiology of this disease is not well understood, but is closely related to age, gender, occupation, metabolism, and injury. The pathological change is a joint lesion caused by degenerative changes in the articular cartilage, mainly osteophytes, and the inflammation of the synovial membrane is a secondary lesion. Second, the cause of knee osteoarthritis 1, chronic strain: long-term poor posture, weight-bearing force, excessive weight, resulting in soft tissue damage to the knee joint. 2, trauma: frequent knee injuries, such as fractures, cartilage, ligament damage. 3. Imbalance of forces on the joint surface: some factors such as trauma, strain or poor posture. Clinical manifestations 1. Slow onset, mostly seen in middle-aged and elderly obese women, often with a history of exertion. 2. The pain is aggravated by knee joint activities, characterized by paroxysmal pain at first, then persistent pain, more so at night and during exertion, and obvious pain when going up and down stairs. 3. The knee joint activity is limited, or even limping. Very few patients may develop interlocking phenomenon or knee joint effusion. 4. There may be popping and grinding sounds when the joint moves, and some patients have swollen joints, and joint deformity can be seen over time. Signs and examinations 1. There is obvious pressure pain at the knee patella, and atrophy of the quadriceps muscle is visible. 2.X-ray film shows hyperplasia of the inner and outer condyles of the tibia and femur, intercondylar spine and calcification of the patellar ligament. 3.Patellar grinding test was positive. Laboratory tests: blood and urine routine are normal, blood sedimentation is normal, anti-O and rheumatoid factor are negative, and joint fluid is non-inflammatory. V. Diagnostic points 1. History of repeated strain or trauma. 2. Knee pain and stiffness, more obvious in the morning when waking up, relieved after activity, aggravated when more activity, relieved after rest. 3. Late pain persists, joint movement is significantly limited, quadriceps muscle atrophy, joint effusion, and even deformity and intra-articular free body. 4. Friction sounds can be detected during knee flexion and extension activities. 5. Frontal and lateral X-rays of the knee joint show lip-like osteophytes on the joint margins of the patella, femoral condyles, and tibial plateau, sharp tibial intercondylar ridge, narrowing of the joint space, dense subchondral bone, and sometimes intra-articular free bodies are seen. 6. Differential diagnosis 1. chondromalacia patellae: the greater the activity of the knee joint, the more pronounced the pain, and there is hyperextension pain and walking weakness. There is pressure pain on the anterior, inferior, medial, lateral and N fossa of the knee. When the knee is extended with pressure on the patella, friction and pain can be palpated. Patellar grinding test is positive. 2. Lateral collateral ligament injury of the knee: there is fixed pressure pain at the site of ligament injury, often at the upper and lower attachment points of the ligament or in the middle. The knee joint is in a semi-flexed position, with limited movement of the joint. Positive lateral squeeze test. 3, knee meniscal injury: history of trauma, post-injury joint pain, swelling, popping and interlocking phenomenon, pressure pain in the internal and external space of the knee. In the chronic phase, the quadriceps muscle atrophy is especially obvious in the medial quadriceps. The McDonald’s sign and grinding test are positive. 4. Subpatellar fat pad injury: history of trauma, strain or cold in the knee. The pain in the knee joint, especially in stairs, is aggravated by knee hyperextension, the pressure pain in the infrapatellar fat pad is obvious, the knee hyperextension test is positive, the patellar tendon relaxation pressure pain test is positive. x-ray lateral knee film, the texture of the fat pad brace is thickened, and a few fat pad calcification shadows are visible. VII. Treatment 1. Non-steroidal analgesic and anti-inflammatory drugs: mainly play an analgesic and anti-inflammatory role, which can effectively relieve pain. 2.Sodium hyaluronate knee cavity injection: sodium hyaluronate knee is the main component of the synovial fluid of the joint cavity, one of the components of the cartilage matrix, which plays a lubricating role in the joint and reduces the friction between tissues. The injection in the joint cavity can significantly improve the inflammatory reaction of the synovial fluid tissue, enhance the viscosity and lubricating function of the joint fluid, protect the joint cartilage, promote the healing and regeneration of the joint cartilage, relieve pain and increase the joint Mobility. It is often injected intra-articularly, 25mg once, once a week for 5 weeks, with strict aseptic operation. 3.Glucosamine: Glucosamine is the most important monosaccharide that constitutes polyglucosamine and proteoglycan in articular cartilage matrix. Normal people can synthesize GS by amination of glucose, but in osteoarthritis, the synthesis of GS in cartilage cells is blocked or insufficient, resulting in softening of cartilage matrix and loss of elasticity, destruction of collagen fiber structure, and increase of cartilage surface lumen to make bones wear and destroy. Glucosamine can block the pathogenesis of osteoarthritis, promote the synthesis of proteoglycans with normal structure in chondrocytes, and inhibit the production of enzymes that damage tissue and cartilage, reduce damage to chondrocytes, improve joint movement, relieve joint pain, and delay the course of osteoarthritis. Take 250-500mg orally once, 3 times a day, best taken with meals. 4, pain point targeting therapy; pain point in Chinese medicine is also called A-Yi point, Tian-Ying point, indefinite point, sensitive point, etc.. Where there is no fixed location and name, to the local pain or pressure point for treatment methods are collectively referred to as pain point targeting therapy or acupuncture point targeting therapy. The main treatment of pain is mostly painful, and its effect is mainly proximal. The main mechanism of the analgesic and anti-inflammatory effect of the A-Yi points is to unblock stagnation and regulate qi and blood, so that the meridians and blood are unblocked and pass through without pain. This type of point makes up for the deficiencies of the 14 meridian points and extra-meridian points in regulating qi and blood. 5.Pain point block and small acupuncture treatment, physiotherapy, etc. 6.Knee arthroscopy. 7.Knee joint replacement: for long-term non-surgical treatment is ineffective, the joint is seriously deformed, and affects the life of those who reliably perform knee joint replacement. 8.SCH triple oxygen scrubbing treatment method: this technology is to use the strong oxidation characteristics of triple oxygen to completely remove the inflammatory factors at the focal area and play an anti-inflammatory and relaxing effect; triple oxygen generates oxygen after oxidation, thus improving blood oxygen saturation, increasing cellular oxygen content, activating metabolism, and promoting the growth and recovery of the body; then help the bone repair and growth, so as to achieve the purpose of treatment.