The location of back pain in liver disease is usually between the horizontal line of the lower angle of the right shoulder blade and the lower edge of the 12th rib, and towards the center up to the midline of the back. Liver disease pain is mainly in the right upper abdominal liver area; because the liver is located roughly on the right side of the body between the 4th and 10th ribs, the corresponding back pain can also appear in a slightly larger area. The main manifestations are dull pain and distension, the location is generally more fixed, and the degree of pain is generally proportional to the severity of liver lesions. The mechanism of pain is generally bad liver, hepatic pericardium tension increases, due to the nerve reflex to the back radiating pain; combined with chronic cholecystitis pain often radiates to the back of the right shoulder. Shoulder and back pain should go to the hospital in time to check the liver function, liver and gallbladder ultrasound, etc., and find out the problem by professional doctors to give timely treatment.