Enlarged inguinal lymph nodes are usually considered to be caused by diseases, such as acute lymphadenitis, nodal disease, malignant lymphoma and so on. Different causes have different treatment methods, and further examination is recommended to clarify the cause of the disease for treatment. 1. Acute lymphadenitis: it can be treated by antibiotics, such as penicillin, erythromycin, lincomycin and other antibiotics, and can also be treated by topical application of medicines, such as ichthyolite ointment, fresh amaranth, Ruyi Jinhuang San, etc., to control the condition and relieve the symptoms. 2. Nodular disease: It can be treated by adrenal glucocorticoid, such as prednisone, methylprednisolone, etc. Anti-malarial drugs, such as chloroquine, hydroxychloroquine, etc., can also be used to inhibit inflammatory reaction and avoid further development of the disease. 3. Malignant lymphoma: it can be treated by chemotherapy, immunotherapy, targeted therapy, such as vincristine, lenalidomide, bortezomib, etc. Surgery can also be performed to remove the tumor or tumor tissue. Enlarged inguinal lymph nodes need to go to the hospital for examination, after clarifying the cause of the disease, combined with the actual situation of the treatment, maintain a good state of mind, regular review, you can take a walk, reduce pressure, improve the body resistance.