Acute progressive glomerulonephritis type III mainly has renal manifestations such as proteinuria, hematuria, edema, hypertension, and decreased renal function, and extra-renal manifestations such as arthralgia, myalgia, irregular fever, pulmonary manifestations such as cough and hemoptysis, and skin manifestations such as rash. Acute progressive glomerulonephritis type III is an oligoimmunodepositing type with no or only trace immunoglobulin deposits in the glomeruli. Most are associated with ANCA-related small vessel vasculitis. Clinically, there are mainly renal manifestations and extra-renal manifestations. 1. Renal manifestations: almost all patients have hematuria, proteinuria of varying degrees, mild hypertension, and occasionally acute hypertension. Some patients have acute nephritis syndrome, with oliguria, anuria, and progressive decrease of renal function to the level of renal failure in the early stage. 2. Extra-renal manifestations: joint pain, myalgia, irregular fever, etc. Lung lesions are mainly manifested as cough, blood in sputum, or even hemoptysis, etc. Skin vasculitis is manifested as purpura, ulcers, nodules, etc.; some patients may have gastrointestinal tract lesions such as intestinal hemorrhage or perforation. Acute glomerulonephritis type III may also have other manifestations, it is recommended to go to the regular hospital in time, under the guidance of the doctor standardized treatment.