Children’s cranial repair is needed to get attention, especially the material of children’s cranial repair, how to be able to effectively treat the important thing is to choose a good surgical material and a team of experts, the next to give you an introduction. Cranial defect is one of the common and diverse human congenital anomalies, which seriously affects the physical and mental health and quality of life of patients, especially large cranial defects caused by trauma, tumor resection and vascular injury. Currently, the common treatments used for cranial bone injuries are autologous bone and allogeneic bone grafting. However, autologous bone grafts often face the challenges of shape matching and limited sources, and allogeneic bone grafts are prone to immune rejection. Because of cranial bone repair surgery, many cranial bone repair materials have also “emerged”, and currently the widely used materials are titanium mesh and PEEK. Although titanium mesh has advantages, there are still many disadvantages. Titanium mesh manufacturers are relatively chaotic, and because of the high technical requirements of titanium alloy processing, so the quality of molding varies, especially for osteoporosis patients, often occurring poor fit. Secondly, titanium mesh is greatly affected by temperature. Moreover, due to the inherent lack of plasticity of titanium mesh, it is difficult to shape titanium mesh perfectly for large curved parts of the head, such as the forehead and the arch of the eyebrow, and there may be traces of mesh after implantation, resulting in a poor visual effect. Compared to titanium mesh, PEEK material is much better. PEEK (polyether ether ketone) is a kind of special engineering plastics, which looks almost the same as ordinary plastics, but it has a lot of advantages such as high temperature resistance, corrosion resistance, robustness, good toughness and fatigue resistance at the same time. It is strong but good elasticity, weight and texture is very close to the human skeleton, even if the collision will not appear concave or deformation, PEEK skull repair perfectly make up for the shortcomings of the titanium mesh. PEEK material is far better than titanium mesh because of the repair, so PEEK is still a more appropriate choice, but also children with cranial defects patients preferred repair material, it is recommended that patients and friends of early treatment, early recovery of health.