Blackheads are mainly caused by the oil secreted by sebaceous glands and clogged at the mouth of hair follicles, which are oxidized by the outside air, and can be removed clinically through general treatment, physical therapy, medication and other methods. 1. General treatment: patients need to pay attention to their daily diet, avoid spicy, stimulating, greasy food, eat less sweets, maintain a happy mood and regular work and rest, avoid staying up late. 2. Physical therapy: patients can remove blackheads through acne needles or acne stickers, etc., and need to avoid excessive squeezing to avoid other infections. Blackheads can also be removed by laser methods such as Intense Pulsed Light (IPL). 3. Medication: Vitamin A acid drugs, such as adapalene gel and tazarotene gel, are often taken in clinic, which can open the mouth of abnormal keratinized hair follicles and discharge the clogged materials to remove blackheads. If blackheads cannot be relieved, patients are advised to seek timely medical treatment for targeted treatment to avoid other adverse consequences. Drugs need to be used under the guidance of a doctor.