Red, swollen and hot lips may be caused by allergy, herpes virus or trauma, etc. The treatment measures for different causes vary, and cause-specific treatments, such as medication, are carried out. 1. Allergy: If the lips are swollen and hot due to contact with allergens such as seafood, mango, eggs, pollen, etc., it is recommended to go to the hospital in time to identify the allergens, cut off the allergens, and then under the guidance of the doctor to use anti-allergy medications such as loratadine, cetirizine, etc. to carry out treatment. 2. Herpes virus: if the herpes simplex virus infection caused by redness, swelling and heat pain of the lips, generally use oral antiviral drugs with topical drugs to treat, such as vasiclovir hydrochloride tablets, acyclovir tablets and other antiviral drugs to inhibit the proliferation of the virus, applying compound lidocaine cream, fusidic acid cream and other symptomatic treatment. 3. trauma: due to bites or mosquito bites caused by red, swollen, hot and painful lips, should avoid local infections, while symptomatic treatment can be. It is recommended that you need to go to the hospital in a timely manner to clarify the causes of red, swollen, hot and painful lips, and the doctor to develop a treatment plan. All of the above drugs should be used under the guidance of a doctor.