High white blood cells and neutrophils and low lymphocytes may be caused by inflammatory diseases, hematologic diseases, etc. They are found in physiological conditions, severe tissue injuries, hemorrhage, poisoning, and so on.
1. In inflammatory diseases caused by bacterial infections (e.g. Streptococcus pneumoniae, etc.), the neutrophils in the body rise compensatory to clear the invading germs and play an anti-inflammatory role, but the lymphocyte counts may be normal or reduced.
2. Hematologic diseases: When acute myeloid leukemia, chronic granulocytic leukemia and other hematologic malignant diseases occur, the bone marrow granulopoiesis is obviously active and generates a large number of leukemia cells released into the peripheral blood, which is manifested as a significant increase in the number of leukocytes and neutrophils, and the majority of the patients have white blood cell counts of more than 50 x 10⁹/L.
However, lymphocyte, erythrocyte and platelet production in the bone marrow of patients with acute myeloid leukemia and chronic granulocytic leukemia are significantly inhibited, i.e., lymphocyte hypoplasia, anemia and reduced platelet counts are manifested.
3. Severe tissue injuries, such as tissue crush injuries and severe burns, can also lead to elevated white blood cell and neutrophil counts.
It is recommended that the patient should consult the hematology department in a timely manner, complete the relevant examinations in order to clarify the specific cause of the disease, and actively treat the cause of the disease.