Venous calculi are most often seen after varicose veins and venous thrombosis, which can be accompanied by a large accumulation of metabolic waste in the blood vessels and gradually form calcified stone-like changes. The venous stones may be dislodged and block the main blood vessels causing serious complications, so clinically most of the stones are removed by medication and surgical treatment. First, when the large blood vessels with venous stone formation, can be through subcutaneous injection of low-molecular heparin, intravenous application of vincristine, blood Cetron and other drugs, oral aspirin to improve the blood circulation in the varicose blood vessels, to promote the dissolution and absorption of metabolic waste and stones on their own. Second, for patients with poor drug treatment of venous stones, the varicose vessels can be surgically removed and the proximal and distal vessels can be anastomosed. Or interventional treatment to remove the venous stones and restore the patency of blood vessels.