Irritating dry cough is one of the typical symptoms of pneumonia, lung cancer, reflux esophagitis, chronic pharyngitis and other diseases. In the early stage of pneumonia, irritating dry cough is the main symptom, and the cough worsens with the progress of the disease, and mucus sputum or pus sputum is coughed up at the same time. The treatment is based on the cause of pneumonia, and antibiotic or antiviral medication is chosen, such as cefixime tablets, ribavirin, levofloxacin tablets and so on. Early stage of lung cancer shows symptoms such as irritating dry cough and hoarseness, which gradually cause emaciation, hemoptysis, dyspnea, dysphagia, etc. It is recommended to be treated as early as possible. Reflux esophagitis with irritating dry cough, accompanied by acid reflux, heartburn, retrosternal pain, etc. The treatment is mainly acid-suppressing therapy, and omeprazole enteric-coated capsule, cimetidine tablets can be given. Chronic pharyngitis can be irritating dry cough in the morning, accompanied by pharyngeal itching, foreign body sensation and other symptoms, the treatment can take compound chlorhexidine gargle. The above drugs need to be standardized and rationally applied under the guidance of professional physicians and pharmacists. If the symptoms fail to improve or even gradually aggravate, it is necessary to consult a regular hospital in a timely manner, and cooperate with the doctor to improve the examination and standardized treatment.