High CA125 is a very important marker of ovarian cancer or gastrointestinal tumor, especially for postmenopausal women, if CA125 is significantly elevated and combined with ovarian or pelvic masses, you should be careful whether ovarian cancer is possible. In early stage of ovarian cancer, surgical resection and postoperative chemotherapy will give a good prognosis for malignant tumors, and a high CA125 should also be careful for the possibility of combined gastrointestinal tumors, such as gastric cancer, pancreatic cancer and colorectal cancer.