There is no clear conclusion on the most painful days after tooth extraction, under normal circumstances, the pain after tooth extraction lasts about 2~3 days, during which gradually reduced, if dry socket disease occurs, there will be severe pain in 2~3 days after tooth extraction, as follows. 1. Under normal circumstances: tooth extraction, trauma caused by metabolic decomposition products and tissue stress response produced by the activation of substances stimulating the nerve endings caused by pain, 2~3 days after the extraction of the pain gradually reduce the disappearance. 2. Dry socket: Severe pain occurs 2~3 days after tooth extraction and radiates to the top of the head and the temporal part of the ear on the same side, which cannot be relieved by general painkillers. At the same time, it is accompanied by corruption and degeneration of blood clots in the alveolar fossa, with a strong putrid odor. If the pain after tooth extraction is severe and continues without relief, it is recommended to go to the hospital in time for targeted treatment.