Callus in medicine refers to callus, toes long callus may and feet by mechanical stimulation, foot deformity and occupation and other factors related to. 1. Mechanical stimulation of the foot: Long-term mechanical stimulation such as extrusion, friction, or inappropriate shoes, long-term pressure on the feet, etc., may trigger excessive proliferation of the skin horny layer, which is prone to callus. 2. Foot deformity: people with foot deformity are more likely to suffer from callus, including bunion, hammer toe and bone spur. 3. Occupation: If you are engaged in an occupation that involves standing and walking for long periods of time, you may develop calluses on your feet. There are more reasons for calloused toes, so patients are advised to seek medical checkups to clarify the causes.