Not necessarily, usually when the dosage of zedoary is 6-10g, there will be no nephrotoxicity, but the improper use of this drug may damage the body, so it is necessary to strictly follow the doctor’s instructions, the correct use of medication. Zedo is the dried tuber of Zedoaceae plant Oriental zedoary or zedoary, sweet, light, cold in nature, belonging to the kidney, bladder meridian, with diuresis and seepage of dampness (to promote the operation of the water to dispel dampness), drainage of heat, turbidity and lipid reduction (to clean up the body of the foul substances, reduce excess body fat) efficacy. Zedoary is often used in urinary dysuria (unsmooth urination), edema and distension, diarrhea and urination, phlegm (pathological products formed by impaired metabolism of water), dizziness, heat drenching (burning and tingling during urination, accompanied by frequent urination and urgent urination, and discomfort of traction in abdomen), astringent pain, and hyperlipidemia. Zedoary in the clinical single flavor of the drug is relatively small, and more and other drugs with other drugs, such as and atractylodes together, can improve the spleen deficiency and dampness caused by gonorrhea (urine and leukorrhea turbid), urinary incontinence, edema and diarrhea. Zedoary and Mutong are effective in treating hemorrhagic gonorrhea (the appearance of blood in the urine accompanied by pain), hot gonorrhea, stony gonorrhea (discharge of gravel during urination, or sudden interruption of urination, pain in the urethra, and unbearable pain in the lower back and abdomen), and astringent pain in short and red urine (small amount of urine, dark yellow in color). This drug is forbidden to be given to those who do not have dampness and heat in the body and those who have kidney deficiency and slippery semen. The adverse effects of Zedoary are not clear, the general dosage of 6-10g, there will be no nephrotoxicity, but its improper use will have an impact on health, if you need to use, please follow the doctor’s instructions, do not self-medication, in order to avoid affecting the health of the body.