Spots on men’s faces can be relieved by sun protection and medication such as hydroquinone cream if caused by melasma, or by vitamin E if caused by age spots. There are different reasons for men to have spots on their face. If it is melasma, it can be manifested as yellowish pigmentation, mostly seen on the prominent part of cheekbones. Lifestyle changes can be made, such as active sun protection and maintaining a good routine. In addition, medication can be used including hydroquinone cream, azelaic acid, and retinoic acid. In addition, older people can have age spots on their face, which can be accompanied by seborrheic keratinization, etc. Vitamin E cream can be used to alleviate the problem, and vitamin C can also be taken orally. If the phenomenon of long spots on the face is obvious, go to the hospital in a timely manner, the use of drugs need to follow the doctor’s instructions.