Urine protein concentration between 0-0.14g/L is within the normal range. When the urine protein quantification is greater than 0.15g/L, it can be called increased urine protein, and the most common clinical test is 24-hour urine protein quantification. When urine protein quantification is greater than 3.5g/L, it is called massive proteinuria, and the most common diseases are nephrotic syndrome and diabetic nephropathy. Urine protein can also be positive in the case of acute glomerulonephritis, chronic glomerulonephritis, hypertensive kidney damage, chronic interstitial nephritis, and vasculitis kidney damage. It is recommended to actively treat the primary disease, such as controlling blood pressure, applying immunosuppressants and other treatments, and regular monitoring is recommended. Because hypertension and urine protein are the two drivers of kidney damage, if not actively treated, abnormal kidney function can occur.