Autologous blood therapy is a method of drawing blood from the patient’s own veins and injecting it under the skin to reduce allogeneic rejection, but it can have many side effects and hazards when treating the disease. The first and greatest hazard is the tendency to experience shortness of breath, purple seizures, and decreased blood pressure, followed by back pain and potentially life-threatening air embolism during treatment. Autoblood therapy can produce non-specific desensitization and promote phagocytosis of leukocytes, thus enhancing the immunity of the body. It is used clinically to treat vitiligo, chronic urticaria, generalized itchy skin, generalized eczema and dermatitis, allergic purpura, psoriasis, and acne. Since blood therapy is only an adjunctive treatment, if it is effective, the treatment can be consolidated by adhering to several courses of injection according to the situation, and if it is not effective, there is no need to continue the injection treatment.