Scientific knowledge of atopic dermatitis

  1. What is atopic dermatitis?  Atopic dermatitis refers to an inflammatory reaction of the skin. The term “atopic” is used to describe several common conditions with a genetic predisposition, such as eczema, asthma, seasonal rhinitis, and cushings fever. Atopic dermatitis can occur anywhere on the body, but the most commonly affected areas are the elbow, N-fold, wrist, and neck (folds). The patient’s (child’s) skin is usually dry and inflammatory reactions occur on it, and repeated scratching can lead to thickening of the skin. Patients (children) often feel itchy on their own.  2. Atopic dermatitis occurs in which age group?  Atopic dermatitis is most common in children, with a prevalence of at least 10% in children, but often gradually improves after childhood. Atopic dermatitis may persist into adulthood, or reoccur after childhood, or it may occur for the first time in adulthood.  3. What are the causes of atopic dermatitis?  It is not fully understood. There is a tendency in some families to be “atopic”, suggesting a role for genetic factors in the pathogenesis. In addition, the barrier function of the skin is often impaired in patients (children), based on which exogenous irritants and allergic substances enter the skin, leading to the occurrence of inflammatory skin reactions.  4.What factors can aggravate atopic dermatitis?  Common factors that aggravate atopic dermatitis include: (1) Environmental factors: Excessive temperature, dust mites, excessive exposure to soap and detergents, etc., can aggravate atopic dermatitis.  (2) Bacterial infections: usually staphylococcal, which can aggravate the inflammatory skin reaction, sometimes even with yellow crusts on the lesions, requiring antibiotic treatment.  (3) Psychological stress: Excessive psychological stress may aggravate atopic dermatitis.  Atopic dermatitis is not contagious.  5. What are the abnormalities in laboratory tests for atopic dermatitis?  (1) Serum IgE levels are often elevated, suggesting an “atopic state”; (2) Peripheral blood eosinophils are often elevated, which is a reference indicator of an “atopic” state; (3) Prick tests often reveal allergies to food, pollen, dust mites, and animal fur. (3) The prick test often reveals allergy to food, pollen, dust mites, animal fur, which helps to find or exclude allergic triggers.  6. Can atopic dermatitis be cured?  It is not curable, but can be well controlled by many methods. In most patients (children), the lesions will improve significantly with age, but the skin will still be dry and uncomfortable.  7. Can atopic dermatitis be inherited?  It is hereditary. The disease tends to run in the same family. If one parent has atopic dermatitis, their children are likely to develop the disease.  8.What are the diseases that can be easily combined with atopic dermatitis?  Patients with atopic dermatitis (children) have a significantly higher rate of other “atopic” diseases such as asthma and allergic rhinitis; for members of a family, if some have atopic dermatitis, others are more likely to have asthma and allergic rhinitis.  In addition to atopic dermatitis, there is a risk of Kaposi chickenpox-like rash with other viruses and systemic symptoms such as fever.  Patients (children) with atopic dermatitis are prone to contact allergy to exogenous substances due to impaired skin barrier function. A portion of adult patients with hand eczema often have atopic dermatitis at the same time.  9. Can vaccination be given to patients (children) with atopic dermatitis?  There are no definite research results and it is recommended that vaccination should not be administered during the acute phase.  10.How should I take care of patients (children) with atopic dermatitis?  Under the guidance of a dermatologist, the patient or parents should: (1) apply emollients and/or moisturizers daily, especially immediately after bathing; (2) use mild, fragrance-free bathing products; (3) avoid bathing too often, for too long, or in too hot water; (4) choose loose clothing made of cotton as much as possible; (5) avoid contact with suspected allergens (pollen, dust mites, animal (5) Avoid contact with suspected allergens (pollen, dust mites, animal fur, etc.).