Redness on the soles of the feet is considered to be related to a number of factors, as follows: First, it is considered to be caused by tinea pedis, which is caused by fungal infections, and common types of fungi include Trichophyton rubrum. The characteristics of the lesions include localized flaky erythema with desquamation, which can appear as blisters. Fungal microscopy or fungal cultures are mostly positive and antifungal medications are usually available, commonly including bifidazole creams. Secondly, the possibility of eczema should also be considered. The specific cause of eczema is unknown and may be related to infectious factors, immune factors, allergic factors, and self-susceptibility. The lesions are characterized by symmetrically distributed erythema, papules, and maculopapular rash with itching. You can choose to take oral antihistamines, commonly known as cetirizine hydrochloride tablets, and topical glucocorticoid creams, commonly known as hydrocortisone butyrate ointment.