There is no uniform clinical time when pregnancy is possible after vaccination. Depending on the method of vaccine preparation, there are mainly inactivated vaccines, live attenuated vaccines, and recombinant protein vaccines, which have different degrees of effects on the body, and therefore the appropriate time for pregnancy varies. The immunogenicity of inactivated vaccines or recombinant protein vaccines for the more common viruses such as new coronaviruses and rubella viruses is relatively weak and usually does not significantly affect the state of pregnancy preparation after vaccination, so it is recommended that couples can prepare for pregnancy 2-3 months after the full vaccination. In contrast, live attenuated vaccine retains some of the active components of the virus, and pregnancy within a short period of time after vaccination may result in the embryo being affected. In addition, HPV vaccine may have certain toxic side effects on the fetus, and the full vaccination takes a long time, so it is recommended that those who have received these vaccines wait 6 months before proceeding to natural pregnancy. Patients who have already discovered pregnancy during this period can go to the hospital to improve the relevant tests to clarify whether there is a potential risk of affecting the fetus and decide whether to continue the pregnancy under the guidance of the doctor.